Reduced glutathione is one of the body’s most important antioxidants and detoxifiers.

Deficiency of reduced glutathione may result in increased free radical oxidation and reduced responsiveness of neutrophilic cells (a type of white blood cell) as part of the cell-mediated immune response.

A study in the Journal of Parenteral Enteral Nutrition showed that patients with stable cirrhosis had significantly lower whole blood reduced glutathione levels when compared to controls.2

Reduced glutathione improves magnesium’s absorption into cells, which is significant since magnesium is involved in over 300 enzymes in the body.3 Reduced glutathione works synergistically with other antioxidants including vitamin C, vitamin E, CoQ10, magnesium, lipoic acid, n-acetylcysteine and selenium.
Vitamin C in the diet greatly enhances the body’s ability to manufacture reduced glutathione.

Supplementation

500-600 mg per day of orally administered reduced glutathione may represent the minimum orally administered dose that could increase blood glutathione levels.
Reduced glutathione intake below 500 or 600 mg is probably not absorbed to any appreciable amounts.
Glutathione levels are best increased by supplementing with vitamin C, glutamine,N-acetyl-cysteine and glycine.
Reduced glutathione given in intravenous form is far more effective clinically.
For information regarding intravenous administration of reduced glutathione consult chapter 15 on intravenous therapies.

http://www.hopeforhepatitisc.com/HealthyLiving/HepC/Part-8.pdf

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