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NEW YORK (Associated Press) - Valeant Pharmaceuticals International
said Thursday that its mid-stage hepatitis C candidate taribavirin
could replace a drug used in a common treatment regimen.
Ribavirin
and peginterferon are considered the standard of care regimen for
hepatitis C. Speaking at the Goldman Sachs Global Healthcare
Conference, Valeant Senior Vice President of Drug Development Harry
Mansbach said that many patients, however, develop anemia upon taking
ribavirin.
Mansbach said that because fewer cases of anemia have
been associated with Valeant's taribavirin drug, it could be prescribed
instead of ribavirin for hepatitis C patients at risk for anemia, such
as those who also are HIV-positive.
Chief Executive J. Michael
Pearson said, though, that the company won't move taribavirin into
late-stage trials until a partner for the drug is found.
Vertex
Pharmaceuticals Inc. and Schering-Plough Corp. also have hepatitis C
drugs in mid-stage development. Both Vertex's telaprevir and
Schering-Plough's boceprevir would be added to standard therapy.
Separately,
Pearson said Valeant is eyeing an application for its late-stage
epilepsy drug retigabine in the third quarter. He noted that following
the release of positive late-stage data in May, partnership interest in
the drug has accelerated.
Over the past six months, Valeant has
been undergoing a strategic restructuring, which has included selling
off some of its drugs, reducing staff and divesting some of its
operations around the world.
On Tuesday, Valeant divested its
Argentina commercial operations for an undisclosed sum. In January, it
sold its hepatitis C drug Infergen to Three Rivers Pharmaceuticals LLC
for about $91.3 million.
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