Spontaneous HCV Clearance in Children | AHCS: Australian Hepatitis C Support

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Spontaneous HCV Clearance in Children

Wednesday, 02 December 2009 15:13 Written by AHCS Team

Approximately 25% of adults exposed to HCV will spontaneously clear the virus without treatment, but it is not clear how often this occurs in children. As reported in the November 2009 Journal of Viral Hepatitis, S.T. Chen and colleagues conducted a long-term follow-up study of 42 children in Taiwan with chronic HCV infection.

Participants were categorized as having high or low HCV viral load at the time of enrollment (above or below 4.5 x 104 IU/mL). Overall, six children (14%) experienced spontaneous viral clearance during a median follow-up period of 10 years.

Children who had low HCV RNA levels at enrollment and during the course of follow-up had a significantly higher likelihood of spontaneous viral clearance in the absence of therapy than those with higher viral loads.

http://www.hcvadvocate.org/news/newsRev ... .11.html#2

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